|
KMID : 1123920020160040729
|
|
Korean Journal of Oriental Physiology and Pathology
2002 Volume.16 No. 4 p.729 ~ p.733
|
|
|
Effect of Insamyangyoung-tang on the Specific Immune Response in BALB/c Mice
|
|
Eun Jae-Soon
Kim Dae-Keun
Oh Chan-Ho
Cui Xun
|
|
|
Abstract
|
|
|
|
The purpose of this research was to investigate the effects of Insamyangyoung-tang water extract (IYT) on the specific immune response in BALB/c mice. When IYT (500mg/kg) was administerd p.o. once a day for 7 days to BALB/c mice, the cell viability of thymocytes and splenocytes was increased. Also, IYT increased the population of CD4/sup +/ cells in thymocytes and the population of Thy1/sup +/ cells and CD4/sup +/ cells in splenocytes. In addition, IYT increased the production of γ -interferon and interleukin-2 from thymocytes and the production of γ -interferon from splenocytes. These results suggest that IYT enhances the specific immune response via activation of Th1 cells in thymocytes and splenocytes.
|
|
|
KEYWORD
|
|
|
Insamyangyoung-tang(人蔘養榮湯), thymocyte, splenocyte, subpopulation, cytokine
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|